HISTORICAL BACKGROUND EDS was noted as early as 400 BC by Hippocrates with descriptions of lax of joint and multiple scars. Formal reports of EDS began in 1657 by Van Meekeren, a surgeon, who described the hyperelasticity of the skin of a sailor
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Acknowledgements This study was supported by grants from the Concerted Research Initiative Ghent University (BOF/GOA 12050698 and BOF/GOA 12.515.04), Interuniversity Attraction Poles Program (Belgian State, Belgian Science Policy, Project P6/35), and FWO Flanders (Project 3G.0052.06)
Archived from the original on July 24, 2019